D-Panthenol 75% (ProVitamin B5) is a clear, viscous liquid raw material with the INCI name Panthenol, made in the USA for moisturizing skin care and conditioning hair care. The specification states a minimum of 75% (R)-panthenol in water, stabilized with 1% D-pantolactone. Choose a 16 oz, 32 oz or 1 gal container, depending on whether you are running bench trials or regular production.
What Is D-Panthenol 75%?
Panthenol is the provitamin form of vitamin B5. This product is a concentrated ingredient, not a finished serum: the figure 75% describes the panthenol content of the supplied liquid, while the amount that goes into a cream, shampoo or mist is a separate decision for the product developer. It has no or only a faint odor, so it does not interfere with the scent of the finished item.
Why Brands Use Provitamin B5
Moisture binding
Panthenol attracts and holds water, which helps skin feel supple and comfortable after application. That makes it a staple in hydrating lotions, face creams and gel textures. For more detail, read our guide D-Panthenol for Scalp Serums: Guide.
Hair conditioning
On hair, provitamin B5 adds moisture and shine and helps strands feel smoother and easier to manage, with less visible frizz. It is a familiar name on shampoo and conditioner labels.
Water solubility
The liquid mixes easily into water-based systems, so there is no need for special solvents or heating to dissolve it.
Applications in Skin and Hair Care
In skin care, panthenol fits daily moisturizers, body lotions, after-sun style gels and light face creams. In hair care it is used in shampoos, rinse-off conditioners, leave-in sprays and scalp tonics. You can see related raw materials in the cosmetic vitamins collection, and the wider active ingredients catalog lists peptides and hyaluronic acid that often appear alongside provitamin B5 on an ingredient list.
How to Use
Add D-Panthenol 75% to the water phase of the product. Because it is very thick, weigh it directly into the beaker rather than measuring by volume, and rinse the spatula into the batch so nothing is lost. Set the input amount according to the technical documentation for the supplied batch and test the finished product for stability, texture and preservation.
Compatibility and Working Tips
Being water-soluble, panthenol combines well with humectants and water-soluble actives. Pairing it with a ready hyaluronic acid gel is a common way to build a hydrating serum base. Very viscous material can cling to container walls in cold rooms; let it reach room temperature before weighing.
Specifications
INCI: Panthenol. Appearance: clear, colorless, viscous liquid with no or faint odor. Content: minimum 75% (R)-panthenol in water, stabilized with 1% D-pantolactone. Solubility: water. Country of origin: USA. Brand: BeautyLabPro. Sizes: 16 oz, 32 oz and 1 gal.
Recipe: Leave-In Hair Mist Base (100 g)
Ingredients: 25 g Lemongrass Hydrosol Organic and 75 g distilled water. Weigh both into a clean beaker and stir. D-Panthenol 75% is then stirred into this base until the liquid is completely clear, at the input level given in the technical sheet for your batch; no amount is stated here because the product card does not specify one. Fill into a fine-mist spray bottle and spray onto towel-dried lengths before styling. Prepare the mist fresh for same-day trials; a product meant for storage needs a preservation system and stability testing.
Storage
Store in the original closed container at room temperature, away from direct sun and heat. Close the lid right after each use.
Stock up in the size that matches your output: 16 oz for development or a full gallon for production lines.
FAQ
Does 75% mean my product will contain 75% panthenol?
No. It describes the supplied liquid. The level in your finished product is set separately.
Is D-Panthenol 75% water-soluble?
Yes. It dissolves in water and is added to the water phase.
Which products can include it?
Lotions, creams, shampoos, conditioners and leave-in hair sprays are typical examples.
Where is it made?
The card lists the USA as the country of origin.








Klara H. –
I’ve been using this product for a few years now and I can’t imagine my skincare routine without it. It’s a true multi-tasker! I use it as a moisturizer, a serum, and even a hair mask. It’s so versatile and it always makes my skin look and feel its best. I highly recommend this product to anyone who wants to achieve healthy, glowing skin!
Jara K. –
I’ve been using this product for a few weeks now and I’m absolutely in love with it! I have dry, sensitive skin and this has been a lifesaver. It’s so hydrating and moisturizing, and it leaves my skin feeling soft and supple. I’ve also noticed that my skin is less red and irritated since I started using it. I highly recommend this product to anyone with dry, sensitive skin!
Emily R., Portland, OR –
D-Panthenol 75% has been a lifesaver for my irritated, dry skin. I mix a few drops into my moisturizer, and it instantly soothes redness and flakiness. My complexion is calmer, softer, and looks more hydrated than ever.
Chris M., Tampa, FL –
I started using D-Panthenol after shaving to calm my skin, and it works better than any aftershave I’ve tried. No more redness or tightness — just smooth, cool skin. Highly recommend for guys with sensitive skin.
Laura G., Charlotte, NC –
This ProVitamin B5 is a staple in our home. I use it in my DIY creams, my husband loves it for sunburn relief, and even my toddler’s skin benefits from it. It’s gentle, powerful, and truly multi-purpose.
Sandra B., Scottsdale, AZ –
I originally bought D-Panthenol for my skin, but now I use it in my hair masks too. It makes my skin feel supple and my hair incredibly soft and full. It’s rare to find something that works so well for both.