BLP Pentapeptide-18 Peptide Solution

BLP Pentapeptide-18 Peptide Solution delivers Pentapeptide-18 in a colorless, translucent water and glycerin base. The source raw material was developed by Lipotec for products that address the look of expression lines on the forehead and around the eyes. It works through a different in vitro pathway than Acetyl Hexapeptide-8, so brands often pair the two in one serum.

What Is BLP Pentapeptide-18 Peptide Solution?

This raw material is based on Leuphasyl from Lipotec, a Pentapeptide-18 solution made in Spain. The supplier describes it as a peptide that targets, in vitro, the mechanism behind expression wrinkles in a new way, which makes it an alternative or a partner to other neuro-type peptides. The INCI is Water (and) Glycerin (and) Pentapeptide-18 (and) Caprylyl Glycol; caprylyl glycol is the preservative in the raw material. If you prefer to work from dry material, the same peptide is also offered on our site as Pentapeptide-18 peptide powder.

Key Properties

A second route for expression lines

Most expression line peptides act on neurotransmitter release in a similar way. Pentapeptide-18 is described as acting on another step of the same process, which is why the supplier reports an additive, synergistic effect with Acetyl Hexapeptide-8 type peptides.

Ready to dose

Because the peptide is already dissolved, there is no weighing of milligram quantities and no dissolving step. You weigh the liquid and stir it into the water phase.

Clean, light appearance

The solution is colorless and translucent, so it does not tint clear gels or white creams.

Where It Is Used

Typical products include forehead serums, eye contour gels, light emulsions and targeted line fillers. A common pairing is a two-peptide serum built with our Acetyl Hexapeptide-8 peptide solution, where each peptide covers its own step. Browse the full peptides category to compare other expression line actives, such as Acetyl Octapeptide-3 and Dipeptide Diaminobutyroyl Benzylamide Diacetate, before you decide on the final blend.

How to Use

Add the Pentapeptide-18 solution at the final stage of production, once the batch has cooled below 40°C (104°F). The supplier recommends a usage rate of 3 to 10%. Stir gently until uniform. Because it is water soluble, it fits gels, serums and the water phase of emulsions without a solubilizer.

Compatibility and Technical Notes

The solution mixes well with humectants such as glycerin and hyaluronic acid and with other water-soluble peptides. Keep it away from heat and long high-shear mixing. The supplier notes that cold storage can occasionally cause the preservative to precipitate; this does not change the integrity of the product, and gentle mixing at room temperature brings it back.

Characteristics

INCI: Water (and) Glycerin (and) Pentapeptide-18 (and) Caprylyl Glycol. Appearance: colorless, translucent solution. Solubility: water. Manufacturer: Lipotec. Country of origin: Spain. Shelf life: at least 18 months when stored as directed. CAS number: not stated by the supplier.

Example: Two-Peptide Forehead Serum (100 g)

Combine 80 g distilled water, 3 g glycerin and 0.4 g hydroxyethylcellulose and stir until a smooth gel forms. At room temperature add 5 g of the Pentapeptide-18 solution, 10 g Acetyl Hexapeptide-8 peptide solution and 1 g of a broad-spectrum preservative suitable for water gels, then top up with water to 100 g. Mix slowly, check the final pH with a meter and fill into 30 mL airless bottles. Test stability before scaling up.

Storage

Keep the original container sealed, protected from light, in a clean, cool place. Refrigeration is preferred. Stored this way, the solution keeps for at least 18 months.

FAQ

How is Pentapeptide-18 different from Acetyl Hexapeptide-8?

They act on different steps of the same in vitro process and are often combined.

How much of the Pentapeptide-18 solution should I add?

The supplier recommends 3 to 10% of the finished product, added below 40°C.

Is it water or oil soluble?

It is water soluble and goes into gels, serums and the water phase of emulsions.

Why does it look cloudy after refrigeration?

The preservative can precipitate in the cold. The supplier states this does not affect the product.