Reduced Glutathione Tripeptide Powder is a white, water-soluble antioxidant built from three amino acids. In cosmetics it is used for a brighter, more even-looking complexion and as part of antioxidant blends.
What Is Glutathione?
Glutathione is a tripeptide built from three amino acids, including glycine and cysteine, and is present in all cells. The supplier describes it as an antioxidant that protects thiol groups in proteins from oxidation. In skin care it is used for brightening products and for an even-looking tone by reducing tyrosinase activity and melanin generation, and for products that address the look of fine lines and elasticity.
Key Properties
Brightening antioxidant
Glutathione is one of the most searched brightening actives and works as an antioxidant in the finished product.
Water soluble
Solubility in water is 20 mg/ml at 25°C according to the supplier, far above the suggested use level.
Works with classic brighteners
The supplier lists vitamin C, arbutin and kojic dipalmitate as compatible partners.
Where It Is Used
Brightening serums, even-tone creams, sheet mask essences, body lotions and freshly mixed powder-to-serum products. Pair it with an antioxidant from our vitamins range and a peptide such as our Acetyl Tetrapeptide-2 solution. More dry peptides can be found in our peptide powders section and in the peptides category.
How to Use
Dissolve in the water phase at room temperature and add at cool-down. Suggested use level: 0.5%. Glutathione is sensitive to oxidation, so mix gently and avoid adding air.
Compatibility and Technical Notes
Reduced glutathione can oxidize in solution over time and may develop a sulfur note. Airless packaging and an antioxidant system help. Combine with vitamin C, arbutin or kojic dipalmitate as the supplier suggests.
Characteristics
INCI: Glutathione. Appearance: white powder. Solubility: water soluble (20 mg/ml at 25°C). Shelf life: 24 months. Use: external, cosmetic and personal care only. CAS number: not stated by the supplier.
Example: Brightening Essence (100 g)
Dissolve 0.5 g Reduced Glutathione Tripeptide Powder and 2 g alpha arbutin in 90.5 g distilled water. Add 3 g glycerin, 3 g D-Panthenol 75% and 1 g preservative. Fill into airless bottles to limit air contact.
Packaging and Freshness
Because reduced glutathione is sensitive to oxidation, many brands sell it as a powder-to-serum kit or in small airless bottles. Making smaller batches more often helps keep the product fresh. A slight change in smell or color over time is a sign that the active has oxidized.
Label the batch date clearly and advise customers to keep the product closed and away from heat.
Storage
Protect from light and store in a cool, dry place in a tightly closed container. Shelf life: 24 months.
FAQ
Is glutathione a peptide?
Yes. It is a tripeptide made of three amino acids.
What use level is suggested?
The supplier suggests 0.5%.
What can I combine it with?
Vitamin C, arbutin and kojic dipalmitate, according to the supplier.


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