Palmitoyl Tripeptide-5 Solution is a liquid source of the small synthetic peptide widely used in collagen-focused skin care. It is clear with a slight opal tint and dissolves straight into water-based products.
What Is Palmitoyl Tripeptide-5 Solution?
According to the supplier, Palmitoyl Tripeptide-5 mimics the skin’s own collagen-building process by activating TGF-β. The supplier links this to improved firmness and elasticity, a smaller look of pores and fewer visible wrinkles, through support of type I and II collagen and fibronectin. Our site also offers Palmitoyl Tripeptide-5 peptide powder for those who prefer to dissolve the peptide themselves.
Key Properties
Collagen-focused positioning
This peptide is mainly used in products about firmness, plumpness and the look of wrinkles.
Heat tolerance
The supplier states it is stable for up to 2 hours at 80°C (167°F), which is unusual for a peptide solution and makes hot processing easier.
Low use level
The suggested rate is only 1 to 3%, so a small bottle covers many test batches.
Where It Is Used
Anti-aging gels, serums, lotions and creams are the main uses. It combines well with our Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 solution and with copper peptide GHK solution when you want a broader collagen story, though copper peptides should be tested for compatibility first. Find more collagen-related actives in our peptides category.
How to Use
Add it to the aqueous phase. Because it tolerates 80°C for up to 2 hours, it can go in with the water phase of a hot emulsion, or be added at cool-down. Suggested usage: 1 to 3%.
Compatibility and Technical Notes
The carrier is water, glycerin and propanediol, preserved with ethylhexylglycerin and benzoic acid. It fits gels, serums and oil-in-water emulsions. Count the glycerin and propanediol in your humectant total.
Characteristics
INCI: Water, Glycerin, Propanediol, Ethylhexylglycerin, Palmitoyl Tripeptide-5, Benzoic Acid. CAS: mixture, as stated by the supplier. Appearance: clear with a slight opal tint. Solubility: soluble in water.
Example: Plumping Peptide Serum (50 g)
Sprinkle 0.15 g sodium hyaluronate into 44 g distilled water and leave to hydrate. Add 2 g glycerin, 1.5 g Palmitoyl Tripeptide-5 Solution, 1.5 g Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 solution and 0.5 g preservative. Stir until uniform and fill into a 30 mL and a 15 mL dropper bottle.
Solution or Powder?
The solution suits small brands and labs that make batches of 1 to 5 kg, because a 1 to 3% rate is easy to weigh on a standard balance. The powder makes sense when you need very high peptide loads or want to choose your own solvent. With the solution, also remember that glycerin and propanediol come along with the peptide, which slightly increases the humectant level of the product.
Storage
The supplier recommends refrigeration at 4°C (39°F). Keep tightly closed between uses.
FAQ
Can Palmitoyl Tripeptide-5 Solution be heated?
Yes. The supplier states it is stable for up to 2 hours at 80°C.
How much should I use?
The suggested usage is 1 to 3% of the finished product.
Is it the same as the powder?
It carries the same peptide, already dissolved in water, glycerin and propanediol.




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