Adifyline Peptide Solution — Acetyl Hexapeptide-38

Adifyline Peptide Solution (Acetyl Hexapeptide-38) is a ready liquid peptide for face and body products aimed at a fuller, smoother-looking appearance. The INCI listing is Butylene Glycol, Water, Acetyl Hexapeptide-38, with 0.05% Acetyl Hexapeptide-38 in solution. Sizes run from a 10 mL sample through 1 oz (30 ml), 4 oz (118 mL), 8 oz (236 mL), 16 oz (473 mL) and 32 oz (946 ml) to 1 gal (3.78 L).

What Is Adifyline?

Adifyline® is the trade name; Acetyl Hexapeptide-38 is the INCI name of the same peptide. While many popular peptides are chosen for firming or expression-line concepts, Adifyline is positioned for volume: contour creams, cheek-area serums and body products built around a plumper look. The ingredient manufacturer has published its own studies on the raw material, but those results describe the ingredient, not any finished product, so claims for your product need their own testing.

Properties of the Solution

Pre-dissolved and easy to dose

Delivered as a clear, colorless to pale yellow liquid, it skips the dissolving step that powders require.

Broad solubility

It is soluble in water, ethanol and glycols, so it fits gels, emulsions and hydroalcoholic textures.

Wide pH window

The stated pH range is 3.0 to 8.0, giving freedom in choosing the rest of the ingredient list.

Applications

Use it in face serums, gel-creams, contour creams, and emulsified body lotions. Developers who build multi-peptide lines often combine it with firming peptides such as Matrixyl 3000 peptide solution or expression-line peptides like Argireline peptide solution. The full selection lives in our active ingredients catalog.

How to Use

The current product data gives a recommended use level of 2% of the total product, added to the water phase. In an emulsion, form the emulsion first and add the peptide once the batch has cooled below 40°C (104°F) to protect it from heat. Then check pH, preservation and stability of the finished product. For more detail, read our guide Acetyl Hexapeptide-38: Use, Compatibility, Mistakes.

Compatibility

Thanks to its water and glycol solubility, the solution blends smoothly with humectants such as a hyaluronic acid gel. Keep processing temperatures low after it is added, and run a small compatibility batch when pairing it with strong acids or other actives.

Specifications

INCI: Butylene Glycol, Water, Acetyl Hexapeptide-38. Active content: 0.05% Acetyl Hexapeptide-38 in solution. Appearance: clear, colorless to pale yellow liquid. Solubility: water, ethanol, glycols. pH range: 3.0 to 8.0. Shelf life: 2 years unopened.

Recipe: Contour Gel Serum (100 g)

Ingredients: 2 g Adifyline Peptide Solution, 30 g hyaluronic acid gel, a broad-spectrum preservative at its supplier’s stated rate, and distilled water to 100 g. Pour the water into a sanitized beaker, add the preservative and stir. Fold in the hyaluronic acid gel until uniform, then add the Adifyline solution last at room temperature. Check the pH, fill into an airless pump and label with a batch number.

Storage

Store cool and dark in the closed original container. Unopened, the shelf life is 2 years.

Start with the 10 mL sample to test your concept, then order the volume that matches your batch, up to a full gallon.

FAQ

Is Adifyline the same as Acetyl Hexapeptide-38?

Yes. Adifyline® is the trade name and Acetyl Hexapeptide-38 is the INCI name.

At what stage should it be added?

Add it to the water phase, and in emulsions only after cooling below 40°C (104°F).

Can I use it in body lotion?

Yes. It works in the water phase of emulsified body lotions and creams.

Which sizes are available?

From a 10 mL sample to 1 gal (3.78 L), with five sizes in between.