Acetyl Tetrapeptide-2 Solution is a liquid firming peptide (INCI: Acetyl Tetrapeptide-2) made in the USA for face serums, lifting creams, eye-contour products, firming masks and neck care. It is added to the water phase at 1 to 5%, and the card lists a shelf life of 24 months after opening. Buy it in sizes from a 10 mL sample through 1 oz, 4 oz, 8 oz, 16 oz and 32 oz to 1 gal (3.78 L).
What Is Acetyl Tetrapeptide-2?
Acetyl Tetrapeptide-2 is a cosmetic-grade peptide supplied here as a liquid solution, for external use only. Because it is a solution rather than a powder, its carrier and active concentration must be considered when you calculate a use level. The current technical details also mention an amber glass bottle with dropper.
Why Choose It
Firming positioning
The peptide is used in products aimed at visibly firmer, more resilient skin with a smoother, more lifted appearance.
Neck and face focus
Lifting creams, face serums and neck-care products are its main applications, which makes it a good fit for mature-skin lines.
Simple water-phase addition
A clear use range and water-phase addition make development straightforward.
Applications
Use it in serums, lifting creams, eye-contour products, firming masks and neck creams. It combines naturally with other firmness-focused peptides such as Palmitoyl Pentapeptide-4 Peptide Solution or Tripeptide-21 Peptide Solution. Explore the full peptides category for more options.
How to Use
Add Acetyl Tetrapeptide-2 Solution to the water phase at 1 to 5%, depending on product type. Compatibility and finished-product performance should be tested in the chosen base, including neck creams. For more detail, read our guide X50 Myocept vs Acetyl Tetrapeptide-2: Which to Use.
Compatibility
The solution suits water-based gels and the water phase of emulsions. A hyaluronic acid gel base is a simple way to build a firming serum. Test any multi-peptide combination in a small batch.
Who uses it
The listing names skin-care developers, cosmetic chemists and beauty entrepreneurs who build their own firming products.
A note on pack sizes
The technical details mention a 4 fl oz amber dropper bottle, while the shop offers seven sizes from a 10 mL sample to 1 gal; confirm the packaging of your chosen size with BeautyLabPro.
Planning the use level
Within the 1 to 5% range, choose the level by product type: a light serum and a rich lifting cream may need different amounts. Remember that the solution’s carrier counts toward the total, so calculate with the solution weight, not the pure peptide.
Shelf life after opening
With 24 months of shelf life after opening, a larger bottle can serve several production runs when kept as directed.
Technical Details
INCI: Acetyl Tetrapeptide-2. Origin: made in USA. Form: liquid solution. Grade: cosmetic, for external use only. Use: water phase, 1 to 5%. Shelf life: 24 months after opening.
Recipe: Firming Neck Gel (100 g)
Ingredients: 4 g Acetyl Tetrapeptide-2 Solution, 22 g hyaluronic acid gel and 74 g distilled water. Stir the gel into the water until even, add the peptide solution and mix gently. Fill into a pump bottle and smooth over the neck and jawline with upward strokes. Without a preservative this is a short-term trial; add a validated preservation system before storing.
Storage
Keep the solution in a cool, dark place; the stated shelf life is 24 months after opening.
Order the 10 mL sample to try it, then choose a larger bottle for production.
FAQ
Is this Acetyl Tetrapeptide-2 a powder?
No, it is a liquid solution.
Can I use it in a neck cream?
Yes, neck-care and facial creams are listed applications.
How much should I add?
1 to 5% in the water phase.
How long does it keep?
24 months after opening, stored in a cool, dark place.


Jessica M., Portland, ME –
I added Acetyl Tetrapeptide-2 to my routine for prevention, but I ended up loving how it made my skin feel more toned and healthy. It gives a subtle lift and bounce, which I didn’t expect so soon. Love that it’s clean and easy to use!
Caroline D., Charleston, SC –
Acetyl Tetrapeptide-2 gave my skin a noticeable lift — especially around the jawline and neck. After just a few weeks, my face looked more sculpted, and the sagging I hated started to fade. It feels light, but the results are real.
Michael B., Reno, NV –
I’ve been using this peptide in my evening serum and I can feel the change. My skin is firmer, especially on the cheeks and lower face. It doesn’t feel heavy or greasy, and it absorbs fast. Definitely something I’ll keep in my routine.
Linda W., Sacramento, CA –
My skin was thinning and losing shape, but this peptide brought back firmness and structure. Even my makeup sits better now. I feel like it’s helping my skin rebuild strength from within. Such a pleasant surprise at my age.