Palmitoyl Pentapeptide-4 Peptide Solution is a clear to slightly hazy, water-compatible liquid (INCI: Palmitoyl Pentapeptide-4) for serums, creams, lotions and eye-area products. Often called a Matrixyl®-type peptide, it is one of the most widely used peptides in modern skin care for smoother, more youthful-looking skin. Sizes run from a 10 mL sample to 1 gal (3.78 L), and every bottle is carefully packaged in the USA.
What Is Palmitoyl Pentapeptide-4?
Palmitoyl Pentapeptide-4 is a palmitoylated peptide offered here as a ready liquid. The solution offers convenient handling, works well with water-based products and is easy to incorporate. It is a cosmetic ingredient for building finished products, not a finished skin-care item itself, and it is for external use only.
Benefits for Your Products
Smoother-looking skin
The peptide is chosen for products that help improve the appearance of fine lines and wrinkles and promote a firmer-looking complexion.
Premium positioning
It integrates easily into modern cosmetic products and is commonly found in professional skin-care lines and luxury serums.
Face, neck and eye area
The listed application areas cover the face, neck and eye-area products, so one ingredient can serve a whole routine.
Applications
Use it in facial serums, creams, moisturizers, eye-care products and other professional skin-care items. It is not the same as Matrixyl 3000: that product pairs Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7, available as Matrixyl 3000 Peptide Solution. See all liquid peptides in the peptides category and more actives in the active ingredients section.
How to Use
Add the solution to water-based systems or the water phase of creams and lotions, using the supplied-grade instructions for processing and use level. Evaluate the finished product for stability and appearance before production. For more detail, read our guide Palmitoyl Pentapeptide-4 Solution: How to Use It.
Compatibility
The solution is water compatible and fits gel serums and emulsions. A pre-hydrated hyaluronic acid gel makes a convenient carrier. Test it together with other peptides in a small batch.
Who buys it
BeautyLabPro supplies this ingredient to developers, estheticians, skin-care brands, laboratories and cosmetic manufacturers across the United States, with a COA available on request and fast US shipping.
Product Information
INCI: Palmitoyl Pentapeptide-4. Appearance: clear to slightly hazy liquid. Solubility: water compatible. Application area: face, neck and eye-area products. Packaging: carefully packaged in the USA. Sizes: 10 mL sample, 1 oz, 4 oz, 8 oz, 16 oz, 32 oz and 1 gal.
Recipe: Neck and Face Peptide Gel Base (80 g)
Ingredients: 24 g hyaluronic acid gel and 56 g distilled water. Fold the gel into the water until clear and smooth. Palmitoyl Pentapeptide-4 solution is added last at the level from the supplied-grade instructions; the card gives no number, so no gram amount is listed. Fill into a pump bottle for evaluation. A product meant for storage also needs a tested preservation system.
Storage
Keep the bottle tightly closed in a cool, dry place, away from direct sunlight and excessive heat. Keep out of reach of children.
Start with the 10 mL sample and step up to the bottle size your production needs.
FAQ
Is it the same as Matrixyl 3000?
No. This is Palmitoyl Pentapeptide-4; Matrixyl 3000-type products contain Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7.
Which products can include it?
Serums, creams, lotions, moisturizers and eye-area products.
What does the solution look like?
A clear to slightly hazy liquid.
Is a COA available?
Yes, on request.


Lorein , Atlanta –
After just a few weeks of using a cream with Palmitoyl Pentapeptide, I can see a noticeable difference in my skin’s firmness and overall appearance. The lines on my forehead and around my mouth are less pronounced, and my skin feels incredibly smooth and hydrated. This peptide has become a staple in my anti-aging routine, and I couldn’t be happier with the results!
Megan, Miami –
I was skeptical about anti-aging products until I tried one with Palmitoyl Pentapeptide. The change in my skin is remarkable! Not only have my fine lines softened, but my skin also looks more radiant and feels much firmer. It’s like I’ve turned back the clock on my complexion. This ingredient is a must-have for anyone serious about skincare.
Nika, CA –
I’ve been using products with Palmitoyl Pentapeptide-4 for a few weeks, and my skin already feels smoother and more hydrated. Fine lines around my eyes and mouth have visibly softened. I love how lightweight it feels, yet it delivers such powerful results. It’s become a must-have in my skincare routine!
Bobby , Texas –
After adding Palmitoyl Pentapeptide-4 to my routine, I noticed a healthier, more refreshed look in the mirror. The texture of my skin became smoother, and some deeper lines began to fade. It absorbs quickly and feels clean on the skin. I didn’t expect such visible improvement from a peptide — but it works.
Veronika ,New York –
As a busy mom in New York, I barely have time for myself, but Palmitoyl Pentapeptide-4 has been a game changer. My skin looks brighter and more rested, even after long days. I’ve gotten compliments at the school pickup line — that never happens! It’s like a little secret weapon in my bathroom cabinet.