Fermentation-Born PDRN for Microbiome Lines
Biofermented PDRN is Sodium DNA made by microbial fermentation, giving you a vegan, “lab-grown” PDRN for microbiome-friendly and fermented-beauty concepts. It is a ready-to-use liquid with a generous use range, from toners to concentrated ampoules.
The Source Behind Biofermented PDRN Solution
Fermentation is a long-standing Korean beauty theme, from fermented essences to postbiotics. This grade brings PDRN into that story without salmon raw materials, and it is supplied pre-preserved with hexanediol and ethylhexylglycerin.
Why Formulators Choose Biofermented PDRN Solution
It is ideal for brands that already sell ferments or postbiotics and want a PDRN line that fits the same philosophy. The wide use range (up to 20%) lets you scale the claim to the price point.
Key Benefits
- Vegan, fermentation-derived PDRN
- Helps skin look balanced, healthy and radiant
- Fits fermented and microbiome-friendly concepts
- Wide use range from toners to ampoules
- Pre-preserved, easy to add at cool-down
Applications
- Fermented essences and first-treatment toners
- Microbiome-friendly serums
- Ampoules
- Scalp care tonics
- Creams and masks
How to Use
Add to the water phase during cool-down, below 40 °C, and stir gently; avoid long heating, strong acids and high-shear mixing after addition. Recommended use level: 1–5% in toners and eye care; 1–10% in essences, creams, lotions and masks; 2–20% in serums, ampoules and scalp care. Use our cosmetic formulation calculators to convert percentages into grams for your batch. This is a raw cosmetic ingredient for use in topical formulations only, not for direct application, injection or use with microneedling or other devices.
Specifications
| INCI (typical — verify with COA) | Water, Butylene Glycol, 1,2-Hexanediol, Sodium DNA, Ethylhexylglycerin |
|---|---|
| Source | Sodium DNA produced by microbial fermentation |
| Form | Water-soluble liquid |
| Appearance (typical) | Clear liquid |
| pH (supplier) | 5.0–8.0 |
| Solubility | Water-soluble; add to the aqueous phase |
| Preservation | Preserved, shelf-stable (full INCI incl. preservative on COA) |
| Recommended use level | 1–5% in toners and eye care; 1–10% in essences, creams, lotions and masks; 2–20% in serums, ampoules and scalp care |
| Country of origin | South Korea |
| Storage | Shelf-stable and preserved. Store tightly closed in a cool, dark place, away from direct sunlight and heat. |
| Shipping | Ships by standard shipping; orders ship the next business day. Free standard US shipping on qualifying orders of $49 or more. |
| Sizes | 10 mL sample, 1 oz (30 mL) and 4 oz (118 mL) |
| Packaging | Amber glass dropper bottle with BeautyLabPro label |
Typical values for this grade. Exact INCI, appearance and pH for your lot are on the Certificate of Analysis supplied with each order; always verify the INCI with the COA before printing labels.
Formulator Tips
- Pair with our Lactobacillus postbiotic actives for a full “ferment + PDRN” story.
- Start at 3–5% in serums; the 20% top end is for concentrated ampoules.
- Contains butylene glycol; adjust other glycols in your formula accordingly.
Pairs Well With
Build a complete formula with our Low Molecular Lactobacillus PDRN Solution, Lacto PDRN 5000 ppm Solution, Multi-Weight Hyaluronic Acid Complex and PDRN and GHK-Cu Serum with Plant Exosomes. Other PDRN solutions: Recombinant Vegan PDRN Solution, Phyto-PDRN Hydrolyzed DNA Solution, PDRN NAD+ Complex.
FAQ
Is it the same as Lacto PDRN?
No. Our Lacto PDRN grades use a Lactobacillus ferment; this grade is a different fermentation-derived Sodium DNA in a butylene glycol base.
Is it vegan?
Yes, the DNA comes from fermentation, not fish. Keep the supplier statement with your COA for label claims.
What is the recommended use level for Biofermented PDRN Solution?
The supplier range is 1–5% in toners and eye care; 1–10% in essences, creams, lotions and masks; 2–20% in serums, ampoules and scalp care. Start at the low end in a test batch and confirm stability in your base.
How should I store and ship Biofermented PDRN Solution?
Shelf-stable and preserved. Store tightly closed in a cool, dark place, away from direct sunlight and heat. Ships by standard shipping; orders ship the next business day. Free standard US shipping on qualifying orders of $49 or more. It ships in 10 mL sample, 1 oz (30 mL) and 4 oz (118 mL) sizes.
More from the range: all PDRN ingredients, exosome solutions, peptide solutions and botanical extracts. Read our guides Plant-Derived PDRN vs Salmon PDRN and PDRN, Exosomes and Peptides in 2026.
For cosmetic manufacturing use only. These statements have not been evaluated by the FDA. This ingredient is not intended to diagnose, treat, cure or prevent any disease and is not for injection or use with microneedling or other medical procedures.




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