Low-Molecular-Weight DNA for Light Textures
Hydrolyzed Sodium DNA is PDRN broken into shorter fragments, the grade often described as low-molecular-weight PDRN. It is a clear, water-thin liquid that disappears into toners, essences and light serums without adding body.
The Source Behind Hydrolyzed Sodium DNA Solution
Hydrolysis splits long DNA chains into smaller pieces, which lowers viscosity and makes the material easy to blend. Many formulators pair it with standard Sodium DNA to tell a “multi-weight PDRN” story, the same way multi-weight hyaluronic acid is marketed.
Why Formulators Choose Hydrolyzed Sodium DNA Solution
It is an affordable way to add a PDRN line to everyday products and a smart partner for regular salmon PDRN. Shoppers are actively searching “sodium DNA vs PDRN,” and this grade lets you answer with both.
Key Benefits
- Helps skin look smoother and feel hydrated
- Very light, water-thin texture
- Lets you build a multi-weight PDRN claim
- Affordable entry into PDRN formulating
- Clear in toners, mists and essences
Applications
- First essences and toners
- Face mists
- Lightweight serums
- Eye serums
- Daily moisturizers
How to Use
Add to the water phase during cool-down, below 40 °C, and stir gently; avoid long heating, strong acids and high-shear mixing after addition. Recommended use level: 0.5–5% in serums and professional products; 0.5–3% in ampoules; 0.2–3% in essences; 0.2–2% in creams and masks; 0.1–1% in eye care. Use our cosmetic formulation calculators to convert percentages into grams for your batch. This is a raw cosmetic ingredient for use in topical formulations only, not for direct application, injection or use with microneedling or other devices.
Specifications
| INCI (typical — verify with COA) | Hydrolyzed Sodium DNA (aqueous solution; full INCI on COA) |
|---|---|
| Source | Hydrolyzed (shorter-fragment) Sodium DNA |
| Form | Water-soluble liquid |
| Appearance (typical) | Clear to slightly opalescent liquid |
| Solubility | Water-soluble; add to the aqueous phase |
| Preservation | Preserved, shelf-stable (full INCI incl. preservative on COA) |
| Recommended use level | 0.5–5% in serums and professional products; 0.5–3% in ampoules; 0.2–3% in essences; 0.2–2% in creams and masks; 0.1–1% in eye care |
| Country of origin | South Korea |
| Storage | Shelf-stable and preserved. Store tightly closed in a cool, dark place, away from direct sunlight and heat. |
| Shipping | Ships by standard shipping; orders ship the next business day. Free standard US shipping on qualifying orders of $49 or more. |
| Sizes | 10 mL sample, 1 oz (30 mL) and 4 oz (118 mL) |
| Packaging | Amber glass dropper bottle with BeautyLabPro label |
Typical values for this grade. Exact INCI, appearance and pH for your lot are on the Certificate of Analysis supplied with each order; always verify the INCI with the COA before printing labels.
Formulator Tips
- Combine with our Salmon PDRN Solution (1:1) for a “multi-weight PDRN” serum.
- Add during cool-down; keep pH 5–7.
- At higher levels check the scent of your base; DNA solutions can have a faint natural note.
Pairs Well With
Build a complete formula with our Multi-Weight Hyaluronic Acid Complex, vitamins and vitamin derivatives, Salmon PDRN Powder and PDRN and GHK-Cu Serum with Plant Exosomes. Other PDRN solutions: Salmon PDRN Solution, PDRN Sodium Solution, Phyto-PDRN Hydrolyzed DNA Solution.
FAQ
What is the difference between Sodium DNA and Hydrolyzed Sodium DNA?
They are the same family. The hydrolyzed grade has shorter fragments and lower viscosity; INCI lists it as Hydrolyzed Sodium DNA.
Is the source salmon?
The supplier does not state the source on the spec; confirm on the COA before making a salmon or vegan claim.
What is the recommended use level for Hydrolyzed Sodium DNA Solution?
The supplier range is 0.5–5% in serums and professional products; 0.5–3% in ampoules; 0.2–3% in essences; 0.2–2% in creams and masks; 0.1–1% in eye care. Start at the low end in a test batch and confirm stability in your base.
How should I store and ship Hydrolyzed Sodium DNA Solution?
Shelf-stable and preserved. Store tightly closed in a cool, dark place, away from direct sunlight and heat. Ships by standard shipping; orders ship the next business day. Free standard US shipping on qualifying orders of $49 or more. It ships in 10 mL sample, 1 oz (30 mL) and 4 oz (118 mL) sizes.
More from the range: all PDRN ingredients, exosome solutions, peptide solutions and botanical extracts. Read our guides Plant-Derived PDRN vs Salmon PDRN and PDRN, Exosomes and Peptides in 2026.
For cosmetic manufacturing use only. These statements have not been evaluated by the FDA. This ingredient is not intended to diagnose, treat, cure or prevent any disease and is not for injection or use with microneedling or other medical procedures.




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